Duc Viet Ho, Hanh Nhu Thi Hoang, Hung Quoc Vo, Khan Viet Nguyen, Ty Viet Pham, Anh Tuan Le, Kiem Van Phan, Hien Minh Nguyen, Hiroyuki Morita & Hoai Thi Nguyen
Journal of Natural Medicines volume 74, pages591–598(2020) Cite this article
DOI: https://doi.org/10.1007/s11418-020-01395-9
Abstract
Three new steroidal saponins, aspiletreins A–C (1–3), together with 2H-chromen-2-one (4), and α-tocopherol (5), were isolated from whole Aspidistra letreae plants collected in Vietnam. Their structures were elucidated by a combination of spectroscopic analyses, including 1D- and 2D-NMR, IR, and HRESIMS, and by comparison with the reported data in the literature. Compounds 1–3 exhibited moderate cytotoxicities against the LU-1, HeLa, MDA-MB-231, HepG2, and MKN-7 human cancer cell lines, with IC50 values ranging from 7.69 ± 0.40 to 20.46 ± 3.11 µM.
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